The CBRC has awarded 8 new project grants this month.
The CBRC received a fantastic response to the funding call made in autumn 2010. After a robust peer review process, grants were awarded to projects from the infectious disease, neurotherapeutics, neurodiagnostics and cardiovascular disease themes.
Funded projects include research to improve diagnosis of viral encephalitis, methods of improving vaccination, new therapies for mitochondrial diseases and evaluation of a novel combination therapy for pulmonary hypertension.
CBRC director Professor Deenan Pillay said: “We are delighted at the range of projects we have been able to fund. These are exciting and cutting-edge proposals, and are an excellent example of the translational potential embedded across the UCLH/UCL partnership.”
See below for full details of the funded projects.
|
Applicant |
Project title |
Lead Theme |
|
Prof Judith Breuer, Dr Katie Ward, Dr Anna Maria Geretti, Dr Frank Mattes, Dr Manj Sandhu, Dr Peter Noberg |
Exploiting genome capture and ultradeep sequencing to improve the diagnosis of viral encephalitis |
Infectious Diseases |
|
Prof Benjamin Chain |
Measuring T cell repertoire perturbation in HIV Infection using high throughout sequencing with in cell RT-PCR |
Infectious Diseases |
|
Prof Mary Collins |
Improving vaccination by targeting and activating dendritic cell subsets |
Infectious Diseases |
|
Prof Michael Duchen, Prof Michael Hanna |
Human myoblast model to develop new therapies for mitochondrial diseases: calcium signalling and mitochondrial turnover as novel therapeutic targets |
Neurotherapeutics |
|
Dr Perry Elliott, Dr Caroline Coats, Dr Rumana Omar |
A randomized placebo controlled trial of trimetazidine therapy in hypertrophic cardiomyopathy |
Cardiovascular Disease |
|
Prof Henry Houlden, Dr Mary Davis, Dr Nick Lench |
Developing Next Generation sequencing to revolutionise the translation of disease genes |
Neurodiagnostics |
|
Prof Paul Kellam, Prof Deenan Pillay, Dr Richard Denner, Dr Ian Williams |
Small molecule latency reactivation and biomarkers for efficacy assessment as a strategy towards a virological cure for HIV infection |
Infectious Diseases |
|
Prof Raymond MacAllister, Dr Adrian Hobbs, Dr Benjamin Schreiber, Dr Gerry Coghlan
|
Clinical evaluation of a novel combination therapy for pulmonary hypertension |
Cardiovascular Disease |
