Dementia

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Dementia

 

The aim of our dementia theme is to develop novel treatments through precision medicine. Our focus on young onset and familial dementias will provide key insights into pathophysiological drivers that accelerate or cause neurodegeneration; and allow analysis of participants in the absence of comorbidity and in at-risk populations, a therapeutic window for intervention before functional decline.

Our sub-themes are interdependent. The genetic studies sub-theme will use biomarkers to determine influence on progression and endophenotypes that will be modelled in induced pluripotent stem cells; the latter will assist identification of novel interventions tested in the clinical applications sub-theme using outputs from the biomarkers of change sub theme.

Our Team: