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Biomedical Research Centre

A partnership between UCL and University College London Hospitals NHS Foundation Trust

NHS National Institute for Health Research

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UCL BioResource

In the UK around 20 million people are said to be living with a chronic disease, including neurological disorders, cardiovascular disease and cancer. Living with these diseases has a major impact on a person’s quality of life and on their family.

The UCL BioResource has been set up to help fight against a range of diseases by supporting research and enabling it to take place quicker and more easily. The initiative is part of a national initiative of eight BioResources across England, funded by the NIHR. Click here to read more about the national initiative.

The UCL BioResource is a research register, establishing a pool of thousands of volunteers with and without health problems who are willing to be approached to participate in research studies investigating the links between genes, the environment, health and disease.

The UCL BioResource is on track to surpass its target of reaching 10,000 volunteers by the end of March 2017 and looks forward to continuing to grow.

Anyone can volunteer to be part of the UCL BioResource, click here to find out more.

There are over 9,600 volunteers in the UCL BioResource who can currently be recalled for participation in research. The majority of our participants live in London, but our cohort includes others from across England. Most of our participants are recruited as patients through clinics from hospitals including University College Hospital, the National Hospital for Neurology and Neurosurgery and the Royal Free Hospital. Our panel of participants is very diverse representing various ages, health backgrounds and demographics.

How we support research

The UCL BioResource has been established to support recruitment to research studies both academic and commercial. The UCL BioResource can identify volunteers who specifically match study criteria based on genetic markers, demographic details such as age or location, and phenotypic details such as medications or conditions. 
If you are interested in having your study supported by the UCL BioResource you should first complete a stage 2 study application form and submit this to the UCL BioResource Coordinator. Upon review, proposals deemed feasible will then be sent onto the UCL BioResource Steering Group for formal approval. 

The UCL BioResource welcomes collaboration with other studies, cohorts and clinicians. Please contact the UCL BioResource to find out more at uclbioresource@ucl.ac.uk

Data UCL BioResource collects 

  • Patient information - as part of participant recruitment the UCL BioResource collects basic demographic and phenotypic information on all volunteers. Medical conditions are coded by ICD10 and medications are coded by British National Formulary reference. Participants also provide consent for the UCL BioResource to access their electronic health records.
  • Genotyping - Affymetrix  - UCL BioResource performs high density genotyping on every participant to provide comprehensive coverage of all common Single Nucleotide Polymorphisms. This analysis is performed on the Affymetrix UK Biobank array.
  • Metabolites – 2,250 participants have had metabolomics profiling performed at Metabolon.