Following open competition, the theme has made the following awards:
2020
|
Dr Gillian Tomlinson |
Immune pathogenesis of post-COVID-19 lung disease |
|
Dr Gabriele Pollara |
Macrophages as drivers of immunopathogenesis in COVID-19 |
| Prof Jerry Brown | Interstitial lung disease in the After COVID-19 Recovery clinical cohort |
| Dr Coziana Ciurtin | Investigating the role of CD8+ T-cell inflammation and atherosclerosis in autoimmunity |
| Prof Liz Jury | Using multi-omic analysis to predict immunogenicity to biological therapies in autoimmunity |
2019
|
Mr Harley Buck, Prof Emma Morris |
Defining the transcriptional profile of limbal epithelial stem cells by RNA sequencing analysis |
|
Prof Emma Morris, Dr Rachel Brown |
Understanding T cell immunity in anti-NMDAR encephalitis: Developing therapeutic tools for neurological autoimmunity |
|
Prof Rachel Chambers, Dr Manuela Plate, Dr Robert Hynds |
Establishing a robust scientific rationale for progressing ATP-competitive mTOR inhibitors as a novel anti-fibrotic strategy in idiopathic pulmonary fibrosis |
|
Dr Vincent Muczynski, Prof Amit Nathwani |
A next generation bispecific antibody with an “off-switch” for a controlled treatment of haemophilia A |
|
Dr Alastair O'Brien |
Repurposing of Simvastatin as an immune-restorative therapy in advanced liver disease |
|
Dr Venkat Reddy |
Understanding the Mechanisms of Refractory Systemic Lupus Erythematosus to Stratify Patients for Novel B-cell Targeted Therapies |
|
Prof Margaret Hall-Craggs, Dr Alan Bainbridge, Dr Timothy Bray |
Optimisation of a multiparametric, quantitative MRI tool for assessment of bone and joint health in inflammatory disease |
|
Prof Mike Ehrenstein, Prof Richard Jenner, Prof Javier Herrero |
Anti-TNF as a molecular scalpel to understand and exploit regulatory T cells for therapy in rheumatoid arthritis |
|
Prof Sergio Quezada, Dr Paul Mulholland |
Mapping the immune landscape to develop novel therapies for glioblastoma |
|
Prof Richard Jenner, Richard Angell, Dr Sally Oxenford |
Target identification for a novel therapeutic agent for inflammatory bowel disease |
|
Prof Stephen Pereira, Dr Douglas Thorburn, Dr Pilar Acedo-Nunez, Dr John Timms, Prof Massimo Pinzani |
Enhanced liver fibrosis and cholangiocarcinoma in primary sclerosing cholangitis (ELF-CCA-PSC study) |
|
Prof Ronjon Chakraverty |
A Human Cell Atlas of Graft-versus-Host-Disease |
|
Dr Reza Motallebzadeh |
Integrating immunological, metabolite and microbiome data to predict clinical outcomes in kidney transplantation |
|
Dr Fausto Andreola, Prof Rajiv Jalan and Dr Gautam Mehta |
Glucocorticoid receptor: A novel biomarker and therapeutic target in acute alcoholic hepatitis |
|
Prof Krista Rombouts |
Identification and validation of targets for novel therapies in PNPLA3 SNP - variant primary Human Hepatic Stellate cells in liver disease |
2018
|
Dr Timothy Bray, Dr Coziana Ciurtin |
Quantitative Imaging Biomarkers of Skeletal Inflammation: Biological Validation and Response Prediction |
|
Prof Jeremy Brown |
Functional consequences of B cell depletion therapy on adaptive immunity to Streptococcus pneumoniae |
|
Dr Siobhan Burns, Dr Steven Henson |
Functional modelling of novel STAT1 variants amenable to gene editing |
|
Dr Coziana Ciurtin, Dr Liz Jury |
Endotyping systemic lupus erythematosus and Sjogren's syndrome in adult a, adolescent and paediatric populations for precision medicine therapeutic approaches - The NUANCE study |
|
Dr Ines Pineda-Torra, Dr Liz Jury, Prof Anisur Rahman and Dr Reecha Sofat |
Interferon regulation of lipid metabolism in autoimmunity: towards patient stratification and identification of novel targets for cardiovascular risk in SLE |
|
Prof Joanna Porter |
Neutrophil activation as a biomarker and therapeutic target in interstitial lung |
|
Dr Laura Shallcross |
Precision prescribing for clinical infection syndromes (PRECISE) |
|
Dr Reecha Sofat |
Determining the clinical utility of measuring complement factor H |
