Radiopharmaceutical Chemistry – Dementia PET

  • New fully operational GMP PET facility. MHRA licensed in 2017. Budget £2,75 million
  • Produced >100 doses of TSPO PET tracer 18F-DPA714. Distribution network: IC, KCL, BSMS
  • £1.2 million grant (PI: N Sharma) for TSPO PET in ALS patients. £400k grant tau tracers
  • New patented PET Chemistry platform – tech evaluation with leading tau tracer company  (Patent WO2014057291A1; Journal of the American Chemical Society, 2018)

Planned/future work:

  • Cyclotron installation & new UK leading Centre for Radiopharmaceutical Chemistry
  • Internationally leading dementia/neuro PET with regional distribution of tracers
  • Translational pipeline of innovative tracers from basics sciences to tissue imaging and PET
Dementia